Although we experience that the brain processes an enormous amount of information; furthermore, we know impressive details about how the brain uses it to react appropriately to stimuli from its environment, we still do not know the details and the underlying general principles how neuronal networks represent, process, and store the information they use. What makes the case worse is that, due to the lack of knowledge of the abstract way of neuronal operation, the so-called ”neural information science” relies on a flawed mathematical foundation. We understand how neurons represent, process, and transfer information [16, 28]. We introduce the appropriate interpretation of information for biology.